Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Applications:

ELISA, IHC

Name of antibody:

TNFRSF9

Immunogen:

Fusion protein of human TNFRSF9

Full name:

TNF receptor superfamily member 9

Synonyms:

ILA; 4-1BB; CD137; CDw137

SwissProt:

Q07011

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

200-300